Homelander's superhuman stats let him damage Deadpool faster than the healing factor can recover, though he cannot truly kill Wade.
Homelander is physically far superior to Deadpool in every stat โ strength, speed, durability, and he has flight and heat vision. His heat vision could continuously burn Deadpool, and his strength lets him tear Wade apart physically. The damage output would exceed Deadpool's healing factor's ability to keep up in real-time.
Deadpool's healing factor means Homelander cannot truly kill him, but Homelander can incapacitate Wade so thoroughly that it constitutes a win. Continuous heat vision application, dismemberment, and throwing body parts in different directions would keep Deadpool out of the fight.
Deadpool's weapons โ guns, swords, explosives โ would bounce off Homelander's skin without effect. Wade has no attack in his arsenal that can damage Homelander, while Homelander has multiple ways to incapacitate Deadpool. The matchup is one-directional in terms of damage dealing.
Deadpool's healing factor makes him truly immortal and he will eventually regenerate from any damage. His unpredictable fighting style and fourth-wall awareness make him difficult to put down permanently.
Homelander's heat vision, strength, and speed let him damage Deadpool faster than the healing factor recovers. His durability means Deadpool's entire arsenal is useless, creating a completely one-sided damage exchange.
Homelander wins the fight through overwhelming physical stats, though he cannot truly kill Deadpool. Wade's weapons cannot penetrate Homelander's skin, while Homelander can continuously incapacitate the regenerating mercenary.
Deadpool also fights
Homelander also fights