Omni-ManvsWolverine

Wolverine's adamantium claws can cut anything, and his healing factor makes him nearly immortal. But Omni-Man fights at a power level that makes these advantages insufficient. A Viltrumite who can crack planets generates enough force to scatter Wolverine's adamantium skeleton across a continent.

Wolverine's healing factor has limits — he has been killed by being fully submerged in adamantium and by having every cell in his body destroyed simultaneously. Omni-Man's attacks approach that level of destruction. A full-speed Viltrumite punch could potentially separate the adamantium skeleton from the biological tissue that regenerates.

Wolverine's claws could theoretically cut Omni-Man's Viltrumite skin, but Logan would need to actually land a hit on someone moving at FTL speeds. The speed differential makes close combat nearly impossible for Wolverine.