Thor obliterates Deadpool repeatedly — Wade's healing factor keeps him alive but can't produce a win.
Same pattern as Deadpool vs. other cosmic-tier heroes: Wade can't die, but he also can't win. Thor's Mjolnir strikes reduce Deadpool to paste, and even Deadpool's impressive healing factor needs time to regenerate from that level of damage.
Thor could also place Mjolnir on Deadpool (who is certainly not worthy) and walk away. Wade would be pinned indefinitely.
Deadpool's immortality means Thor can never truly finish him. Wade's unpredictability and fourth-wall awareness might create unexpected situations.
Thor obliterates Deadpool with every strike. Mjolnir pin is an unbreakable containment. The power gap makes Deadpool's weapons completely irrelevant.
Thor wins overwhelmingly in every exchange. Deadpool survives through immortality but has no path to victory.
Deadpool also fights
Thor (Norse) also fights