Patrolling the world's oceans for over 400 million years of evolutionary refinement, the great white shark is nature's most efficient killing machine. Armed with 300 serrated teeth and electroreceptors that detect a heartbeat from yards away, nothing in the sea is safe. A single bite delivers up to 18,000 newtons of force—enough to chomp through bone like breadsticks.

Don't let the pudgy appearance fool you—the hippopotamus is widely considered the most dangerous large animal in Africa, killing more humans annually than lions, leopards, and crocodiles combined. Its massive jaws open to a terrifying 180-degree angle and generate 1,800 PSI of bite force through foot-long canine teeth. At 4,000 pounds, it can outrun most humans on land and is absurdly agile in water.