The tyrannical ruler of Apokolips and one of the most powerful beings in the DC multiverse, Darkseid exists on a level that makes Superman sweat. His Omega Beams can disintegrate, teleport, or resurrect any target and literally cannot miss—they follow you through time and space until contact. He seeks the Anti-Life Equation not because he needs more power, but because even gods crave the ultimate cheat code.

The Mad Titan of Marvel's cosmic hierarchy, Thanos is obsessed with universal balance and willing to snap half of existence out of reality to achieve it. Even without the Infinity Gauntlet, he can trade blows with the Hulk and outthink Reed Richards. With it, he is essentially God—capital G—with a chin that could cut diamonds.