SaitamavsThanos

Saitama's serious punch has casually countered galaxy-level attacks. Thanos at base has tanked planetary-level damage. The raw output gap actually favors Saitama, even before considering his meta-character invincibility.

Thanos's intelligence is his best asset — he could theoretically find ways to work around Saitama's punch. But Saitama's power isn't a puzzle to solve; it's a narrative absolute. He wins in one punch because that's his character concept.

With the Infinity Gauntlet, Thanos could potentially counter Saitama's power through reality manipulation. But at base, the Mad Titan is in the same weight class as opponents Saitama has one-shot.