Don't let the pudgy appearance fool you—the hippopotamus is widely considered the most dangerous large animal in Africa, killing more humans annually than lions, leopards, and crocodiles combined. Its massive jaws open to a terrifying 180-degree angle and generate 1,800 PSI of bite force through foot-long canine teeth. At 4,000 pounds, it can outrun most humans on land and is absurdly agile in water.

Known as the killer whale despite technically being the world's largest dolphin, the orca is the ocean's most intelligent and ruthless predator. Hunting in pods with coordinated strategies that include creating waves to wash seals off ice floes, they've been observed killing great white sharks purely for their livers. The apex predator of apex predators—nothing in the sea hunts an orca.